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Table 9 Bayesian method estimates of indirect probabilities of passing different visual acuity thresholds at month 1 for patients with BRVO on scale of GENEVA trial

From: Indirect comparisons of ranibizumab and dexamethasone in macular oedema secondary to retinal vein occlusion

Improvement or worsening at Month 1

Probability for Group§ (95% CrI)

Relative risk* (95% CrI)

 

Ranibizumab

Dexamethasone

 

Gain ≥15 letters

0.260 (0.140,0.414)

0.213 (0.168,0.261)

0.82 (0.45,1.47)

Gain ≥5 letters and <15 letters

0.453 (0.317,0.593)

0.470 (0.413,0.526)

1.04 (0.74,1.45)

Loss <5 letters and gain <5 letters

0.264 (0.163,0.385)

0.257 (0.209,0.308)

0.97 (0.61,1.57)

Loss ≥5 letters and <15 letters

0.018 (0.002,0.055)

0.057 (0.034,0.086)

3.27 (0.60,17.70)

Loss ≥15 letters

0.005 (0.000,0.025)

0.003 (0.000,0.012)

0.62 (0.02,18.40)

  1. §Mean of 100000 samples from posterior distributions of probability for change in BCVA from baseline category.
  2. *Ratio of mean probabilities with credible interval based on Delta method on log scale.