From: Estimating time-to-onset of adverse drug reactions from spontaneous reporting databases
Naive estimator | TBE | ||||||
---|---|---|---|---|---|---|---|
λ | p | n | BIAS() | MSE() | BIAS() | MSE() | NPM |
0.05 | 0.25 | 100 | 0.498 | 0.250 | 0.030 | 0.005 | 224 |
500 | 0.498 | 0.248 | 0.007 | 0.001 | 79 | ||
0.05 | 0.50 | 100 | 0.195 | 0.038 | 0.008 | 0.001 | 85 |
500 | 0.193 | 0.037 | <0.001 | <0.001 | 1 | ||
0.05 | 0.80 | 100 | 0.073 | 0.005 | <0.001 | <0.001 | 2 |
500 | 0.072 | 0.005 | <0.001 | <0.001 | 0 | ||
1 | 0.25 | 100 | 10.06 | 102 | 0.462 | 2.17 | 72 |
500 | 9.95 | 99 | 0.046 | 0.48 | 10 | ||
1 | 0.50 | 100 | 3.91 | 15.4 | 0.126 | 0.49 | 29 |
500 | 3.86 | 14.9 | -0.022 | 0.12 | 0 | ||
1 | 0.80 | 100 | 1.45 | 2.16 | 0.004 | 0.11 | 0 |
500 | 1.45 | 2.11 | 0.004 | 0.02 | 0 |