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Table 3 Results from simulations based on MIST2 dataset (OR = 0.23)

From: Accounting for centre-effects in multicentre trials with a binary outcome – when, why, and how?

  Mean treatment effect Power (%) Convergence (%)
Unadjusted for centre-effects 0.20 66.5 97.1
Fixed-effects 0.19 65.0 96.3
Random-effects 0.19 66.0 96.1
GEE 0.20 66.5 98.0
Mantel-Haenszel 0.22 50.3 95.9