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Table 5 Estimates of prevalence (P), intracluster correlation coefficients (ICC), their respective 95% CI, design effect (Deff), and mean cluster size (n a ) for categorical variables of process during pregnancy

From: Intracluster correlation coefficients for the Brazilian Multicenter Study on Preterm Birth (EMIP): methodological and practical implications

Variable

P(%)

ICC

95% CI for ICC

Deff

na

Hospitalization

22.3

0.030

0.008-0.052

10.0

265

Reasons for hospitalization:

     

   Emesis

0.6

0.006

0.001-0.013

2.3

264

   Uterine contraction

5.7

0.014

0.002-0.026

5.3

264

   Amniorrhexis

2.2

0.009

0.001-0.017

4.0

264

   Bleeding

2.6

0.008

<0.001-0.016

3.0

264

   Maternal disease

8.9

0.029

0.007-0.050

10.1

264

   Fetal disease

0.8

0.028

0.007-0.049

6.0

264

Syphilis

1.6

0.004

<0.001-0.009

1.7

265

Anemia (registered)

32.0

0.070

0.023-0.118

24.1

238

Treatment for anemia

52.6

0.283

0.138-0.428

74.8

213

Short cervix (US)

1.4

0.011

<0.001-0.022

4.0

209

Cervical insufficiency

2.1

0.005

<0.001-0.012

2.6

230

Cerclage

1.4

0.019

0.003-0.034

5.6

238

Uterine anomalies

0.6

<0.001

<0.001-0.003

0.6

237

Fibroid

1.9

0.002

<0.001-0.006

1.5

233

Maternal diseases:

     

   Diabetes

5.7

0.027

0.006-0.047

7.8

254

   Gestational hypertension

7.7

0.025

0.006-0.045

9.4

254

   Preeclampsia/eclampsia/HELLP

16.2

0.062

0.019-0.104

22.5

254

   Chronic hypertension

5.7

0.007

<0.001-0.014

2.8

254

   Other chronic infection

0.7

0.010

0.001-0.020

4.5

254

   Thyroid diseases

1.6

0.027

0.006-0.047

8.2

254

   Renal disease

1.2

0.008

<0.001-0.015

3.1

254

   Sickle cell anemia

0.3

0.002

<0.001-0.006

1.5

254

   Other chronic anemia

0.5

<0.001

<0.001-0.003

0.7

254

   Cardiac disease

1.1

0.003

<0.001-0.008

1.9

254

   Lung disease

1.5

0.009

<0.001-0.017

3.8

254

   Epilepsy

0.6

0.001

<0.001-0.004

1.5

254

   Systemic lupus erythematous

0.5

0.020

0.004-0.036

4.6

254

   Other collagenoses

0.2

0.001

<0.001-0.004

1.4

254

   Digestive disease

0.6

0.006

<0.001-0.013

3.1

254

   Bariatric surgery

<0.1

<0.001

<0.001-0.003

0.8

254

   Psychiatric disease

1.0

0.015

0.003-0.028

5.4

254

   Orthopedic disease

0.2

<0.001

<0.001-0.003

0.9

254

   Neoplasms

0.2

0.001

<0.001-0.004

1.4

254

   Thrombosis or thrombophilia

0.4

0.006

<0.001-0.013

2.4

254

Fetal malformation

5.5

0.146

0.057-0.236

35.9

246

Fetal growth restriction

9.3

0.019

0.004-0.035

6.9

246

Other fetal morbidity

7.4

0.386

0.219-0.554

101.5

246

Triplets

2.0

<0.001

<0.001-0.030

1.0

22

Infertility treatment

4.4

<0.001

<0.001-0.031

0.9

22

Multiple monochorionic pregnancy

35.8

0.046

<0.001-0.111

2.0

18

Multiple monoamniotic pregnancy

5.8

0.038

<0.001-0.098

1.9

18

Twin-to-twin transfusion syndrome

5.4

<0.001

<0.001-0.036

0.9

18