TY - JOUR AU - Smaïl-Faugeron, Violaine AU - Fron-Chabouis, Hélène AU - Courson, Frédéric AU - Durieux, Pierre PY - 2014 DA - 2014/05/11 TI - Comparison of intervention effects in split-mouth and parallel-arm randomized controlled trials: a meta-epidemiological study JO - BMC Medical Research Methodology SP - 64 VL - 14 IS - 1 AB - Split-mouth randomized controlled trials (RCTs) are popular in oral health research. Meta-analyses frequently include trials of both split-mouth and parallel-arm designs to derive combined intervention effects. However, carry-over effects may induce bias in split- mouth RCTs. We aimed to assess whether intervention effect estimates differ between split- mouth and parallel-arm RCTs investigating the same questions. SN - 1471-2288 UR - https://doi.org/10.1186/1471-2288-14-64 DO - 10.1186/1471-2288-14-64 ID - Smaïl-Faugeron2014 ER -