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Table 6 Median number of patients classified correctly or misclassified under each decision rule for diagnosis of Latent Tuberculosis Infection (LTBI)

From: A Bayesian framework for estimating the incremental value of a diagnostic test in the absence of a gold standard

Decision Rule Classified correctly Misclassified Incremental value compared to LTBI if TST + (%)
  TP (%) TN (%) Total FN (%) FP (%) Total  
India study (n = 719)
LTBI if TST+ 280 (39) 331 (46) 611 (85) 100 (14) 8 (1) 108 (15) -
LTBI if TST + and QFT+ 223 (31) 335 (47) 558 (78) 158 (21) 3 (1) 161 (22) -7
LTBI if TST + or QFT+ 347 (48) 326 (46) 673 (94) 33 (4) 13 (2) 46 (6) 9
Portugal study (n = 1218)
LTBI if TST+ 504 (41) 245 (20) 749 (61) 70 (6) 399 (33) 469 (39) -
LTBI if TST + and QFT+ 361 (30) 634 (52) 995 (82) 213 (17) 10 (1) 223 (18) 21
LTBI if TST + or QFT+ 528 (43) 243 (20) 771 (63) 46 (4) 401 (33) 447 (37) 2
  1. TP = true positive; FP = false positive; FN = false negative; TN = true negative.