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Table 6 Median number of patients classified correctly or misclassified under each decision rule for diagnosis of Latent Tuberculosis Infection (LTBI)

From: A Bayesian framework for estimating the incremental value of a diagnostic test in the absence of a gold standard

Decision Rule

Classified correctly

Misclassified

Incremental value compared to LTBI if TST + (%)

 

TP (%)

TN (%)

Total

FN (%)

FP (%)

Total

 

India study (n = 719)

LTBI if TST+

280 (39)

331 (46)

611 (85)

100 (14)

8 (1)

108 (15)

-

LTBI if TST + and QFT+

223 (31)

335 (47)

558 (78)

158 (21)

3 (1)

161 (22)

-7

LTBI if TST + or QFT+

347 (48)

326 (46)

673 (94)

33 (4)

13 (2)

46 (6)

9

Portugal study (n = 1218)

LTBI if TST+

504 (41)

245 (20)

749 (61)

70 (6)

399 (33)

469 (39)

-

LTBI if TST + and QFT+

361 (30)

634 (52)

995 (82)

213 (17)

10 (1)

223 (18)

21

LTBI if TST + or QFT+

528 (43)

243 (20)

771 (63)

46 (4)

401 (33)

447 (37)

2

  1. TP = true positive; FP = false positive; FN = false negative; TN = true negative.