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Table 2 EQ-5D-5L profile of patients by GOLD grade

From: Measuring health-related quality of life in chronic obstructive pulmonary disease: properties of the EQ-5D-5L and PROMIS-43 short form

 

Total sample [n (%)]

GOLD 1 (mild; n = 102) [n (%)]

GOLD 2 (moderate; n = 353) [n (%)]

GOLD 3 (severe; n = 165) [n (%)]

GOLD 4 (very severe; n = 50) [n (%)]

p-value (comparing GOLD 1,2 vs 3,4)

EQ-5D dimension

 Mobility

     

0.003†

  No problems

244 (36.4)

44 (43.1)

141 (39.9)

41 (24.9)

18 (36.0)

 

  Slight problems

179 (26.7)

28 (27.5)

93 (26.4)

46 (27.9)

12 (24.0)

 

  Moderate problems

189 (28.2)

25 (24.5)

92 (26.1)

58 (35.2)

14 (28.0)

 

  Severe problems

52 (7.8)

5 (4.9)

25 (7.1)

16 (9.7)

6 (12.0)

 

  Extreme problems

6 (0.9)

0 (0)

2 (0.6)

4 (2.4)

0 (0)

 

 Self-care

     

<.0001‡

  No problems

539 (80.5)

87 (85.3)

297 (84.1)

127 (77.0)

28 (56.0)

 

  Slight problems

88 (13.1)

13 (12.8)

43 (12.2)

23 (13.9)

9 (18.0)

 

  Moderate problems

34 (5.1)

2 (2.0)

9 (2.6)

11 (6.7)

12 (24.0)

 

  Severe problems

5 (0.8)

0 (0)

4 (1.1)

0 (0)

1 (2.0)

 

  Extreme problems

4 (0.6)

0 (0)

0 (0)

4 (2.4)

0 (0)

 

 Usual activities

     

<.0001†

  No problems

303 (45.2)

61 (59.8)

175 (49.6)

56 (33.9)

11 (22.0)

 

  Slight problems

183 (27.3)

22 (21.6)

96 (27.2)

49 (29.7)

16 (32.0)

 

  Moderate problems

135 (20.2)

13 (12.8)

64 (18.1)

44 (26.7)

14 (28.0)

 

  Severe problems

32 (4.8)

4 (3.9)

12 (3.4)

10 (6.1)

6 (12.0)

 

  Extreme problems

17 (2.5)

2 (2.0)

6 (1.7)

6 (3.6)

3 (6.0)

 

 Pain/discomfort

     

0.26†

  No problems

255 (38.1)

35 (34.3)

131 (37.1)

62 (37.6)

27 (54.0)

 

  Slight problems

207 (30.9)

33 (32.4)

118 (33.4)

48 (29.1)

8 (16.0)

 

  Moderate problems

160 (23.9)

27 (26.5)

81 (23.0)

42 (25.5)

10 (20.0)

 

  Severe problems

43 (6.4)

7 (6.9)

21 (6.0)

11 (6.7)

4 (8.0)

 

  Extreme problems

5 (0.8)

0 (0)

2 (0.6)

2 (1.2)

1 (2.0)

 

  Anxiety/depression

     

0.15†

 No problems

427 (63.7)

63 (61.8)

237 (67.1)

101 (61.2)

26 (52.0)

 

  Slight problems

139 (20.8)

20 (19.6)

64 (18.1)

41 (24.9)

14 (28.0)

 

  Moderate problems

79 (11.8)

16 (15.7)

40 (11.3)

15 (9.1)

8 (16.0)

 

  Severe problems

20 (3.0)

2 (2.0)

11 (3.1)

5 (3.0)

2 (4.0)

 

 Extreme problems

5 (0.8)

1 (1.0)

1 (0.3)

3 (1.8)

0 (0)

 
  1. GOLD = Global initiative for chronic Obstructive Lung Disease.
  2. Based on †Chi-square, or ‡Fisher’s exact test.
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BMC Medical Research Methodology

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