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Table 2 EQ-5D-5L profile of patients by GOLD grade

From: Measuring health-related quality of life in chronic obstructive pulmonary disease: properties of the EQ-5D-5L and PROMIS-43 short form

  Total sample [n (%)] GOLD 1 (mild; n = 102) [n (%)] GOLD 2 (moderate; n = 353) [n (%)] GOLD 3 (severe; n = 165) [n (%)] GOLD 4 (very severe; n = 50) [n (%)] p-value (comparing GOLD 1,2 vs 3,4)
EQ-5D dimension
 Mobility       0.003
  No problems 244 (36.4) 44 (43.1) 141 (39.9) 41 (24.9) 18 (36.0)  
  Slight problems 179 (26.7) 28 (27.5) 93 (26.4) 46 (27.9) 12 (24.0)  
  Moderate problems 189 (28.2) 25 (24.5) 92 (26.1) 58 (35.2) 14 (28.0)  
  Severe problems 52 (7.8) 5 (4.9) 25 (7.1) 16 (9.7) 6 (12.0)  
  Extreme problems 6 (0.9) 0 (0) 2 (0.6) 4 (2.4) 0 (0)  
 Self-care       <.0001
  No problems 539 (80.5) 87 (85.3) 297 (84.1) 127 (77.0) 28 (56.0)  
  Slight problems 88 (13.1) 13 (12.8) 43 (12.2) 23 (13.9) 9 (18.0)  
  Moderate problems 34 (5.1) 2 (2.0) 9 (2.6) 11 (6.7) 12 (24.0)  
  Severe problems 5 (0.8) 0 (0) 4 (1.1) 0 (0) 1 (2.0)  
  Extreme problems 4 (0.6) 0 (0) 0 (0) 4 (2.4) 0 (0)  
 Usual activities       <.0001
  No problems 303 (45.2) 61 (59.8) 175 (49.6) 56 (33.9) 11 (22.0)  
  Slight problems 183 (27.3) 22 (21.6) 96 (27.2) 49 (29.7) 16 (32.0)  
  Moderate problems 135 (20.2) 13 (12.8) 64 (18.1) 44 (26.7) 14 (28.0)  
  Severe problems 32 (4.8) 4 (3.9) 12 (3.4) 10 (6.1) 6 (12.0)  
  Extreme problems 17 (2.5) 2 (2.0) 6 (1.7) 6 (3.6) 3 (6.0)  
 Pain/discomfort       0.26
  No problems 255 (38.1) 35 (34.3) 131 (37.1) 62 (37.6) 27 (54.0)  
  Slight problems 207 (30.9) 33 (32.4) 118 (33.4) 48 (29.1) 8 (16.0)  
  Moderate problems 160 (23.9) 27 (26.5) 81 (23.0) 42 (25.5) 10 (20.0)  
  Severe problems 43 (6.4) 7 (6.9) 21 (6.0) 11 (6.7) 4 (8.0)  
  Extreme problems 5 (0.8) 0 (0) 2 (0.6) 2 (1.2) 1 (2.0)  
  Anxiety/depression       0.15
 No problems 427 (63.7) 63 (61.8) 237 (67.1) 101 (61.2) 26 (52.0)  
  Slight problems 139 (20.8) 20 (19.6) 64 (18.1) 41 (24.9) 14 (28.0)  
  Moderate problems 79 (11.8) 16 (15.7) 40 (11.3) 15 (9.1) 8 (16.0)  
  Severe problems 20 (3.0) 2 (2.0) 11 (3.1) 5 (3.0) 2 (4.0)  
 Extreme problems 5 (0.8) 1 (1.0) 1 (0.3) 3 (1.8) 0 (0)  
  1. GOLD = Global initiative for chronic Obstructive Lung Disease.
  2. Based on Chi-square, or Fisher’s exact test.