Measuring health-related quality of life in chronic obstructive pulmonary disease: properties of the EQ-5D-5L and PROMIS-43 short form

Table 5 Correlations between clinical and HRQL measures

	% pred. FEV₁	FACIT- Dyspnea	mMRC dyspnea	Borg dyspnea (at rest)	Borg dyspnea (during 6MWT)	6MWD	EQ-5D index	EQ-VAS
% pred. FEV₁	1
FACIT-dyspnea	-0.36	1
mMRC dyspnea	-0.29	0.59	1
Borg dyspnea (at rest)	-0.13	0.46	0.33	1
Borg dyspnea (during 6MWT)	-0.26	0.56	0.48	0.36	1
6MWD	0.28	-0.44	-0.45	-0.25	-0.34	1
EQ-5D index	0.19	-0.58	-0.48	-0.38	-0.37	0.46	1
EQ-VAS	0.26	-0.43	-0.41	-0.34	-0.35	0.29	0.55	1
P-PF	0.32	-0.71	-0.62	-0.39	-0.58	0.56	0.68	0.51
P-A	-0.09	0.42	0.23	0.27	0.23	-0.19	-0.46	-0.33
P-D	-0.08	0.45	0.25	0.26	0.29	-0.19	-0.49	-0.34
P-F	-0.09	0.58	0.43	0.38	0.42	-0.29	-0.55	-0.48
P-SD	0.02^†	0.35	0.28	0.26	0.23	-0.10	-0.37	-0.31
P-SR	0.18	-0.57	-0.41	-0.37	-0.42	0.37	0.54	0.47
P-PI	-0.01^†	0.41	0.33	0.31	0.22	-0.29	-0.65	-0.37
P-P	0.01^†	0.35	0.26	0.27	0.21	-0.29	-0.58	-0.33

6MWD = six-minute walk distance; 6MWT = six-minute walk test; FACIT = Factional Assessment of Chronic Illness Therapy; FEV₁ = forced expiratory volume in 1 second; mMRC = modified Medical Research Council; PROMIS = Patient Reported Outcomes Measurement Information System; P-PF = PROMIS-Physical Function; P-A = PROMIS-Anxiety; P-D = PROMIS-Depression; P-F = PROMIS-Fatigue; P-SD = PROMIS-Sleep Disturbance; P-PI = PROMIS-Pain Interference; P-P = PROMIS-Pain intensity scale; P-SR = PROMIS-Satisfaction with participation in Social Roles.
^†Spearman’s rank correlation coefficient p > 0.05 (not significant).

ISSN: 1471-2288