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Table 3 R D ( t ) estimated with different methods at months 13, 32 and 60

From: Model-based estimation of measures of association for time-to-event outcomes

  RD
  13 32 60
R D(t): Cox prop 3.7%; (−1.2%;7.7%) 5.7%; (−1.2%;12.3%) 5.8%; (−1.2%;12.7%)
R D(t): Cox TD 0.1%; (−6.8%;6.5%) 6.5%; (−1.5%;14.1%) 7.7%; (−0.5%;15.6%)
RD: PV identity Z const 2.2%; (3.5%;−7.9%) 2.2%; (3.5%;−7.9%) 2.2%; (3.5%;−7.9%)
R D(t): PV identity Z TD −1.6%; (−8.5%;5.3%) 4.6%; (−3.2%;12.4%) 6.2%; (−1.4%;13.7%)
  1. Cox prop: CGPM with a Cox model without treatment time dependent effect; Cox TD: CGPM with a Cox model with treatment time dependent effect; PV identity Z const: Pseudo-value model with identity link and constant treatment effect RD; PV identity Z TD: Pseudo-value model with identity link and time dependent treatment effect. B-splines were used to model treatment time dependent effects