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Table 1 Hypothetical data for a binary marker from a nested case-control study

From: Markers for early detection of cancer: Statistical guidelines for nested case-control studies

 

Marker -

Marker +

Total

No cancer

990

10

1000

Cancer

20

80

100

  1. True positive rate (TPR) = 80/100 = .80 = sensitivity False positive rate (FPR) = 10/1000 = .01 = 1 – specificity
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