From: Interim analyses of data as they accumulate in laboratory experimentation
Number of pairs | Nominal critical Pvalue | Adjusted actual Pvalue (P') | |
---|---|---|---|
 |  | (binomial) | (continuous normal) |
1 | 0.050 | 0.050 | 0.050 |
10 | 0.050 | 0.055 | 0.194 |
20 | 0.050 | 0.107 | 0.248 |
50 | 0.050 | 0.171 | 0.320 |
100 | 0.050 | 0.227 | 0.374 |