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Table 4 Association between early study experience and failure to complete study*

From: Participant characteristics associated with withdrawal from a large randomized trial of spermicide effectiveness

Experience during first 6 weeks Total Did not complete study Relative Risk (95% confidence interval)
  N n %  
Completed at least one follow-up visit     
   yes 925 203 21.9 0.68 (0.53 – 0.87)
   no 170 55 32.4 1
Completed at least one pregnancy test within first 4 weeks     
   yes 1070 250 23.4 0.73 (0.41 – 1.31)
   no 25 8 32.0 1
Provided diary information for each day     
   yes 958 215 22.4 0.71 (0.54 – 0.94)
   no 137 43 31.4 1
Used spermicide at every coital act     
   yes 739 153 20.7 0.70 (0.57 – 0.87)
   no 356 105 29.5 1
Of those who completed follow-up visit     
   Reported medical complaints     
yes 437 104 23.8 1.17 (0.92 – 1.50)
no 488 99 20.3 1
   Disliked spermicide somewhat or a lot     
yes 52 12 23.1 1.05 (0.63 – 1.76)
no 873 191 21.9 1
   Distrusted contraceptive efficacy     
yes 209 51 24.4 1.15 (0.87 – 1.52)
no 716 152 21.2 1
   Disliked timing of application     
yes 435 96 22.1 1.01 (0.79 – 1.29)
no 490 107 21.8 1
   Complained about messiness     
yes 375 76 20.3 0.88 (0.68 – 1.13)
no 550 127 23.1 1
   Had problems with insertion     
yes 465 105 22.6 1.06 (0.83 – 1.35)
no 460 98 21.3 1
   Reported that partner disliked spermicide     
yes 208 52 25.0 1.18 (0.90 – 1.56)
no 717 151 21.1 1
   Happy with spermicide     
yes 408 80 19.6 0.82 (0.64 – 1.05)
no 517 123 23.8 1
  1. *Includes only participants in the analysis for at least 6 weeks
  2. Did not dislike spermicide, had no side effect/AE, and had a satisfied partner