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Figure 3 | BMC Medical Research Methodology

Figure 3

From: Estimating the mean and variance from the median, range, and the size of a sample

Figure 3

An example: Meta Analysis with all eligible trials included. Cochrane investigators [5] were only able to pool two studies to evaluate the effect of Epo on change in hemoglobin in the patients with the baseline level of hemoglobin >12 g/dl who underwent chemotherapy. Their results show that on average Epo increases hemoglobin by 2.05 g/dl. Using our estimation formulas, we were able to include two other studies eligible for this meta-analysis ([9, 10]). The pooled estimate decreased to 1.22 g/dl, i.e., a decrease of approximately 40%.

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