From: How does study quality affect the results of a diagnostic meta-analysis?
 | Univariate analysis | Multivariate analyis | ||
---|---|---|---|---|
Variable* | RDOR (95% CI) | p-value | RDOR (95% CI) | p-value |
Ultrasound for the detection of reflux: weighted (n = 28 studies) | ||||
Use of contrast enhanced ultrasound: yes vs no | 23.9 (9.8, 58.8) | <0.001 | 8.0 (2.9, 22.0) | <0.001 |
Ultrasound for the detection of reflux, with ultrasound type forced into the model: weighted (n = 28 studies) | ||||
Appropriate reference standard: yes vs unclear + | 0.2 (0.0, 1.0) | 0.047 | Dropped$ | Â |
Disease progression bias avoided: yes vs unclear | 3.5 (1.4, 9.2) | 0.011 | 1.4 (1.0, 1.9) | 0.033 |
Withdrawals accounted for: yes vs unclear | 3.2 (1.2, 8.5) | 0.020 | 2.8 (1.1, 6.9) | 0.027 |
Withdrawals accounted for: no vs unclear | (0.4, 0.1, 1.7) | 0.175 | 0.6 (0.1, 2.8) | 0.502 |
Ultrasound for the detection of reflux: unweighted (n = 28 studies) | ||||
Use of contrast enhanced ultrasound: yes vs no | 29.8 (13.5, 65.8) | <0.001 | 29.8 (13.5, 65.8) | <0.001 |
Ultrasound for the detection of reflux, with ultrasound type forced into the model: unweighted (n = 28 studies) | ||||
Appropriate reference standard *: yes vs unclear | 0.2 (0.0, 1.2) | 0.075 | Dropped | Â |
Partial verification bias avoided: yes vs no | 4.1 (1.1, 14.8) | 0.034 | 4.1 (1.1, 14.8) | 0.034 |