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Table 2 Boundaries c α and for two to four stages

From: Adaptive designs based on the truncated product method

Number of stages (k)

c α

for Ď„ = 0.5

α = 0.025

2

0.00380

0.00408

3

0.00072

0.00085

4

0.00015

0.00020

α = 0.05

2

0.00870

0.00948

3

0.00184

0.00222

4

0.00042

0.00057

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BMC Medical Research Methodology

ISSN: 1471-2288

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