Table 4 Meta-analysis of all trials and high-quality trials from evidence-based practice guidelines
| Â | Â | Â | Practice Guideline | ||
|---|---|---|---|---|---|
| Â | Â | Â | Colon Cancer Adjuvant chemotherapy Outcome: Mortality (32) | Head & Neck Concomitant therapy Outcome: Mortality (31) | Systemic Therapy erythropoietin Outcome: need for blood transfusion (34) |
All Studies | # studies (# comparisons) | 11 (11) | 18 (20) | 15 (15) | |
|  |  | OR (CI) | 0.82 (0.62 – 1.09) | 0.62 (0.54 – 0.72) | 0.57 (0.47–0.70) |
High Quality Studies By Assessment Scale Criteria | Jadad (3-item) range = 0–5 criteria >2 | # studies (# comparisons) | 0 | 2 (2) | not applied |
|  |  | OR (CI) | - | 0.54 (0.34 – 0.86) |  |
|  | Jadad (6-item) range = 0–8 criteria >3 | # studies (# comparisons) | 8 (8) | 13 (14) | 9 (9) |
|  |  | OR (CI) | 0.88 (0.69–1.13) | 0.53 (0.44 – 0.64) | 0.57 (0.44–0.72) |
|  | Sindhu (41-item) range = 0–79.5 criteria > 44.8 | # studies (# comparisons) | 9 (9) | 11 (12) | not applied |
|  |  | OR (CI) | 0.86 (0.68–1.09) | 0.62 (0.49 – 0.79) |  |
|  | Downs & Black (13-item) range = 0–13 criteria > 7 | # studies (# comparisons) | 6 (6) | 12 (14) | not applied |
|  |  | OR (CI) | 0.86 (0.59–1.25) | 0.56 (0.46 – 0.68) |  |