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Table 2 Genetic relationship between the woman who undergoes the pregnancy and offspring in each conception group and predicted patterns of association between prenatal risk factor X and outcome Y for a) environmentally mediated and b) genetically mediated effects.

From: Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects

  

Association between X and Y

 

Genetic relationship Between pregnant woman and offspring

Environmental Mediation

Genetic Mediation

Homologous IVF

Yes

yes

yes

Sperm donation

Yes

yes

yes

Embryo donation

No

yes

no

Egg donation

No

yes

no

Gestational Surrogacy

No

yes

no