TY - JOUR AU - Loke, Yoon K. AU - Price, Deirdre AU - Herxheimer, Andrew AU - the Cochrane Adverse Effects Methods Group PY - 2007 DA - 2007/07/05 TI - Systematic reviews of adverse effects: framework for a structured approach JO - BMC Medical Research Methodology SP - 32 VL - 7 IS - 1 AB - As every healthcare intervention carries some risk of harm, clinical decision making needs to be supported by a systematic assessment of the balance of benefit to harm. A systematic review that considers only the favourable outcomes of an intervention, without also assessing the adverse effects, can mislead by introducing a bias favouring the intervention. SN - 1471-2288 UR - https://doi.org/10.1186/1471-2288-7-32 DO - 10.1186/1471-2288-7-32 ID - Loke2007 ER -