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Table 7 Outcome comparisons in effect sizes: Sensitivity analyses (SA)

From: Assessing the order of magnitude of outcomes in single-arm cohorts through systematic comparison with corresponding cohorts: An example from the AMOS study

Analysis

Median

Interquartile range

Ranges: Number (percentage) of comparisons

N (total)

N

   

≤ -0.8

-0.79 to -0.5

-0.49 to -0.2

-0.19 to 0.19

0.2 to 0.49

0.5 to 0.79

≥ 0.8

Comparisons

Cohorts

Main analysis: any design, setting, intervention, and baseline status

0.11

-0.11 to 0.35

13 (3)

20 (4)

58 (11)

214 (41)

142 (27)

53 (10)

17 (3)

517 (100)

84

SA1: Design: only observational studies (excluding randomised controlled trials)

0.08

-0.14 to 0.28

6 (2)

11 (4)

40 (13)

140 (47)

77 (26)

21 (7)

6 (2)

301 (100)

44

SA2: Setting: only primary care/health maintenance organization

0.24

0.03 to 0.38

3 (2)

4 (3)

9 (7)

42 (30)

60 (43)

16 (12)

4 (3)

138 (100)

27

SA3: Intervention: only drugs, physiotherapy, other physical therapy, or mixed

0.08

-0.09 to 0.30

3 (1)

7 (2)

36 (11)

164 (50)

86 (26)

21 (6)

8 (2)

325 (100)

49

SA4: Baseline status: only comparisons with small baseline difference (< 0.50 standard deviation)

0.08

-0.13 to 0.28

5 (1)

14 (4)

41 (12)

161(47)

81 (24)

29 (9)

9 (3)

340 (100)

81

SA1 + SA2 + SA3 + SA4

0.07

-0.03 to 0.19

0 (0)

0 (0)

2 (13)

10 (63)

3 (19)

0 (0)

1 (6)

16 (100)

5