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Table 2 Factors influencing harm reported in the abstract

From: Abstracts in high profile journals often fail to report harm

 

cPR (CI95%)

Funding*

 

   drug or device companies

1

   public institutions

0.77 (0.60 to 0.97)

Placebo

 

   other control

1

   placebo

0.97 (0.81 to 1.13)

Sample size

 

   less than 20

1

   equals or more than 200

1.14 (0.96 to 1.33)

Direction of effect

 

   beneficial to intervention

1

   neutral or against the intervention

1.00 (0.83 to 1.19)

Harm in text

 

   no harm in text

1

   harm in text

8.71 (5.90 to 12.01)

Clinical significance of harm

 

   no mortality nor composite in text

1

   mortality or composite in text

1.43 (1.22 to 1.65)

Harm in text statistically significant

 

   not statistically significant

1

   statistically significant

1.70 (1.47 to 1.92)

  1. cPR: Prevalence Ratio estimated by logistic regression, and corrected by applying the method proposed by Zhang [24]; CI: Confidence Intervals with error type I equals 5%; *363 articles except for funding in which sample size was n = 226