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Table 1 Pathological prognostic factors and clinical stage at presentation for women with breast cancer living in affluent and deprived areas (whole sample and questionnaire respondents)

From: The impact of consent on observational research: a comparison of outcomes from consenters and non consenters to an observational study

  AFFLUENT n (%) DEPRIVED n (%) Chi squared test result
PATHOLOGICAL PROGNOSTIC FACTORS
SIZE* WHOLE SAMPLE
n = 136
CONSENTED SAMPLE
n = 72
WHOLE SAMPLE
n = 194
CONSENTED SAMPLE
n = 91
WHOLE SAMPLE CONSENTED SAMPLE
0 – 19 mm 70 (51.5%) 42 (58.3%) 106 (54.6%) 54 (59.3%) X 2 = 0.53 X 2 = 0.04
20 – 49 mm 62 (45.6%) 29 (40.3%) 81 (41.8%) 36 (39.6%) DF = 2 DF = 2
>50 mm 4 (2.9%) 1 (1.4%) 7 (3.6%) 1 (1.1%) p = 0.76 p = 0.98
GRADE* n = 110 n = 59 n = 156 n = 72   
1 17 (15.5%) 9 (15.3%) 30 (19.2%) 18 (25.0%) X 2 = 0.66 X 2 = 1.83
2 67 (60.9%) 39 (66.1%) 92 (59.0%) 42 (58.3%) DF = 2 DF = 2
3 26 (23.6%) 11 (18.6%) 34 (21.8%) 12 (16.7%) p = 0.72 p = 0.34
NODAL STATUS* n = 128 n = 72 n = 196 n = 93   
Positive 48 (37.5%) 24 (33.3%) 72 (36.7%) 28 (30.1%) X 2 = 0.01 X 2 = 0.196
Negative 80 (62.5%) 48 (66.6%) 124 (63.3%) 65 (69.9%) DF = 1
p = 0.88
DF = 2
p = 0.736
CLINICAL STAGE AT PRESENTATION
  n = 156   n = 260    
Early 146 (93.6%) 100% 220 (84.6%) 100% X 2 = 7.42 N/A
Locally advanced or metastatic 10 (6.4%)   40 (15.4%)   DF = 1
p = 0.006
 
  1. * Size, grade and nodal status only potentially available for the 366 women (146 affluent and 220 deprived) who had operable breast cancer.
  2. *Total n for whole sample < 366 due to missing data
  3. **Total n for consented sample < 177 due to missing data