Skip to main content

Table 6 Microarray Gene Expression data results (n = 2009 genes, m = 3 replicates)

From: Comparison of two dependent within subject coefficients of variation to evaluate the reproducibility of measurement devices

(a) Technical replicate

 

Affymetrix (l = 1)

Amersham (l = 2)

 

Estimate

SE

Estimate

SE

μ l

2759

150.5

3.74

0.22

ρ l

0.94

0.002

0.99

0.0003

θ l

0.58

0.03

0.25

0.015

σ l

1603

17.88

0.93

0.01

ρ 12 = 0.51, Twald = 11.85, LRT = 122, PM = -7.89 (p < 0.001 for all tests) The estimate of the common WSCV under the null is 0.31 (SE = 0.014) 95% CI for (θ12): (0.28, 0.39)

(b) Biological replicate

 

Affymetrix (l = 1)

Amersham (l = 2)

 

Estimate

SE

Estimate

SE

μ l

2819

142.6

3.43

0.18

ρ l

0.91

0.003

0.93

0.0025

θ l

0.71

0.037

0.63

0.034

σ l

2003.7

22.35

2.16

0.02

ρ 12 = 0.50, Twald = 2.35, LRT= 8.56, PM = -9.04 (p < 0.02 for all tests) The estimate of the common WSCV under the null is 0.67 (SE = 0.025) 95% CI for (θ12): (0.014, 0.15)