Responsiveness of five condition-specific and generic outcome assessment instruments for chronic pain

Table 2 Comparison of the responsiveness of the scales within the same construct domains

Domain	Higher responsiveness	Lower responsiveness	ES	p(ES)	SRM	p(SRM)	r base	r diff
Pain	MPI pain severity	Pain NRS	0.85 vs 0.62	< 0.001	0.72 vs 0.57	0.001	0.76	0.64
Pain	MPI pain severity	SF-36 bodily pain	0.85 vs 0.72	0.053	0.72 vs 0.60	0.027	0.59	0.41
Pain	SF-36 bodily pain	Pain NRS	0.72 vs 0.62	0.144	0.60 vs 0.57	0.606	0.52	0.34
Role interference with pain	MPI interference with pain	SF-36 role physical	0.64 vs 0.65	0.892	0.67 vs 0.40	< 0.001	0.23	0.27
Social interference with pain	MPI interference with pain	SF-36 social functioning	0.64 vs 0.54	0.050	0.67 vs 0.54	0.015	0.50	0.40
Function	SF-36 physical functioning	MPI activity	0.41 vs 0.15	< 0.001	0.47 vs 0.20	< 0.001	0.09	0.18
Affective health: depression	MPI negative mood	SF-36 mental health	0.61 vs 0.54	0.169	0.65 vs 0.66	0.842	0.73	0.40
Affective health: depression	SF-36 mental health	HADS depression	0.54 vs 0.43	0.004	0.66 vs 0.59	0.180	0.73	0.53
Affective health: depression	MPI negative mood	HADS depression	0.61 vs 0.43	0.001	0.65 vs 0.59	0.296	0.61	0.42
Affective health: anxiety	SF-36 mental health	HADS anxiety	0.54 vs 0.35	< 0.001	0.66 vs 0.45	< 0.001	0.72	0.47
Affective health: anxiety	MPI negative mood	HADS anxiety	0.61 vs 0.35	< 0.001	0.65 vs 0.45	< 0.001	0.68	0.37
Coping (control)	MPI control pain	CSQ control pain	0.46 vs 0.30	0.011	0.44 vs 0.29	0.011	0.60	0.33

NRS: Numeric Rating Scale, SF-36: Short Form 36, MPI: Multidimensional Pain Inventory, HADS: Hospital Anxiety and Depression Scale, CSQ: Coping Strategies Questionnaire. ES: Effect Size, SRM: Standardized Response Mean. p: Type I error of the modified Jacknife test comparing two ES or two SRM. r base: bivariate Spearman rank correlation of the baseline scores, r diff: bivariate Spearman rank correlation of the effects (raw score differences baseline → follow-up)

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