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Table 3 Reporting characteristics of population stratification for 315 randomly selected HuGE articles (2001–2003)

From: Reporting of Human Genome Epidemiology (HuGE) association studies: An empirical assessment

Reporting characteristic Count Percent
Explicitly stated that all study participants were drawn from the same ethnic population   
   Unclear 130 41.3
   Stated 185 58.7
Analysis conducted by using different ethnic groups   
   No 285 90.5
   Yes 30 9.5
If different ethnic groups were included, how was ethnicity treated in the analysis (n = 30)   
   Stratified by or adjusted for ethnic groups 23 76.7
   Pooled ethnic groups together 2 6.7
   Unclear 5 16.6
Reported that unlinked genetic markers were used to identify population stratification   
   No 313 99.4
   Yes 2 0.6
Reported that cases and controls were drawn from the same population in regards to geography (n = 227)   
   No 79 34.8
   Yes 148 65.2
Reported that cases and controls were drawn from the same population in regards to the clinical population (n = 227)   
   No 180 79.3
   Yes 47 20.7
Reported that cases and controls were drawn from the same population in regards to the general population (n = 227)   
   No 167 73.6
   Yes 60 26.4
Reported unclear or no information regarding the population from which cases and controls were drawn (n = 227)   
   No 142 62.6
   Yes 85 37.4