Systematic review | Search date | Primary study* (Database entry date)†| Personal communication with review authors or other researchers at the publishing institutions | |||
---|---|---|---|---|---|---|
 |  | Davydov 1994 [14]‡ | Catarino 2000 [13] | Song 2003 [26] | Jeschke 2004 [19] |  |
 |  | (M: 1994-09-01; C) | (M: 2001-01-13) | (M: 2002-12-24; E) | (M: 2004-02-06; E; C) |  |
Reviews considering RCTs and non-RCTs | Â | Â | Â | Â | Â | Â |
Costa/MUHC TAU 2005 [30] | 3/2005 | Not reported (not applicable§) | Non-RCT | Non-RCT | Not reported (PC: excluded) | Jeschke 2004. PC (V. Costa): "Considered not eligible. Although negative pressure was used in one group, we considered that the main intervention studied was the Integra grafting and not vacuum-assisted closure. Moreover, since the group using VAC was a combined intervention (Integra + VAC), we were not sure if this would influence the results making it not an adequate estimate of the results with VAC alone. For these reasons the study was considered ineligible." |
IQWiG 2006 [8] | 5/2005 | Excluded: not NPWT (non-RCT)|| | Excluded: historical control (non-RCT) | Excluded: historical control (non-RCT) | Excluded: outcomes in the test group possibly affected by the additional intervention (RCT) | Davydov 1994. A translation of the full text of this Russian-language article showed that the intervention was not a technique comparable to NPWT. Consequently, IQWiG did not include this study. No reference to a randomised allocation was found. Jeschke 2004. NPWT was applied in combination with fibrin glue-anchored Integra in the test group receiving NPWT, but not in the control group receiving standard therapy; therefore the outcomes in the test group may have been affected by the additional intervention. Consequently, IQWiG did not include this study |
Pham/ASERNIP-S 2006 update/[31]¶ | 10/2004 (RCTs/non-RCTs) 7/2005 (RCTs) | RCT | Non-RCT | Non-RCT | RCT | Davydov 1994. PC (C. Perera): "Allocation not stated, assumed that a valid method of randomisation had been utilised (critical appraisal in the full accelerated systematic review drew attention to this)" Jeschke 2004. PC (C. Perera): "Agree with IQWiG comments regarding additional intervention. Suggest that this RCT was included due to a paucity of RCT evidence on this indication (skin grafts), and as the other included RCT for skin grafts had only a 7 day follow up." |
Reviews considering only RCTs | Â | Â | Â | Â | Â | Â |
Samson/AHRQ 2004 [29](6/2004; RCT) | 6/2004 | Not reported (not applicable**) | Not reported (not applicable**) | Not reported (not applicable**) | Not reported (PC: not identified) | Jeschke 2004. PC (D. Samson): "This study did not appear in our literature search, probably because it was not yet entered onto an electronic database by the date of our last search update." |
OHTAC [32](3/2006; RCT) | 3/2006 | Not reported (not applicable**) | Not reported (not applicable**) | Not reported (not applicable**) | Not reported (PC: excluded) | Jeschke 2004. PC (Medical Advisory Secretariat): "...was included in the literature search results, but there were only twelve patients in the study so it was excluded. The exclusion was not documented in the HTA." |