Univariable analyses | Multivariable analyses | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Clinical reading | Optimized interpretation | Clinical reading | Optimized interpretation | |||||||||||||
Sensitivity Specificity† | Likelihood ratios‡ | Sensitivity Specificity† | Likelihood ratios‡ | Sensitivity Specificity† | Likelihood ratios‡ | Sensitivity Specificity† | Likelihood ratios‡ | |||||||||
Variables | Main effect | Interaction | Main effect | Interaction | Main effect | Interaction | Main effect | Interaction | Main effect | Interaction | Main effect | Interaction | Main effect | Interaction | Main effect | Interaction |
HPV test | <0.001 | 0.03 | <0.001 | 0.033 | <0.001 | 0.18 | <0.001 | 0.18 | <0.001 | 0.09 | <0.001 | 0.011 | <0.001 | 0.15 | <0.001 | 0.17 |
Study setting | <0.001 | 0.10 | 0.001 | 0.11 | <0.001 | - | 0.023 | - | <0.001 | 0.14 | 0.015 | - | <0.001 | - | ||
Age | 0.001 | 0.06 | - | 0.07 | 0.04 | - | 0.12 | - | 0.026 | - | 0.045 | - | 0.047 | - | ||
Current smoking | 0.03 | - | - | - | - | - | - | - | ||||||||
European origin | <0.001 | - | - | - | 0.17 | - | - | - | ||||||||
Educational level | <0.001 | 0.035 | - | 0.043 | 0.014 | - | - | - | ||||||||
Postmenopausal | - | - | - | - | - | 0.17 | - | - | ||||||||
Contraceptive status | - | - | - | - | - | - | - | - |