Table 2 Probability of verification used in the simulations for each decile of the diagnostic test result
Decile of diagnostic test result | Probability of having the gold standard result (%) | ||
|---|---|---|---|
10% verified | 30% verified | 60% verified | |
Probabilities of verification likely to be encountered in a screening study | |||
1 | 0.6% | 3.0% | 16.0% |
2 | 0.9% | 4.9% | 23.9% |
3 | 1.5% | 7.8% | 34.2% |
4 | 2.5% | 12.2% | 46.1% |
5 | 4.1% | 18.7% | 58.5% |
6 | 6.5% | 27.5% | 69.9% |
7 | 10.3% | 38.5% | 79.3% |
8 | 15.9% | 50.7% | 86.3% |
9 | 23.8% | 62.9% | 91.2% |
10 | 34.0% | 73.7% | 94.5% |
Probabilities of verification were adjusted such that false negatives were more (less) likely to be present for 10% (60%) verified | |||
1 | 6.4% | -- | 0.0% |
2 | 7.0% | -- | 0.0% |
3 | 7.7% | -- | 0.1% |
4 | 8.5% | -- | 7.6% |
5 | 9.3% | -- | 92.4% |
6 | 10.2% | -- | 99.9% |
7 | 11.1% | -- | 100.0% |
8 | 12.1% | -- | 100.0% |
9 | 13.2% | -- | 100.0% |
10 | 14.4% | -- | 100.0% |