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Table 3 Analysis of day 14 IgG levels (mg/dl) for the IVIG trial

From: Analysis of neonatal clinical trials with twin births

Birth weight stratum

Analysis

Estimated correlation

Estimated treatment difference

Standard error

95% Confidence interval

501 to 1000 g

ANOVA

N/A

194.05

10.47

(173.50,214.61)

 

LMEM

0.41

194.24

10.42

(173.78,214.71)

(n = 743 babies)

GEE

0.44

194.34

10.37

(174.02,214.65)

1001 to 1500 g

ANOVA

N/A

177.23

10.21

(157.20,197.26)

 

LMEM

0.54

179.79

10.03

(160.11,199.47)

(n = 1267 babies)

GEE

0.36

178.74

10.06

(159.03,198.46)

  1. Randomization was done independently for twins. The multiple gestation rates were 15% and 16% for the 501 to 1000 g babies and 1001 to 1500 g babies, respectively.