Table 2 Analyses to be performed in the IPD meta-analyses.
Topics | Postmenopausal bleeding | Preterm birth | Tubal pathology | Ovarian response in IVF |
|---|---|---|---|---|
ROC analysis | -TVS* | -Cervical length* | -Age* | -Age* |
| Â | Â | Â | -CAT* | -FSH* |
| Â | Â | Â | Â | -AFC* |
| Â | Â | Â | Â | -AMH* |
Univariable analyses | All relevant patient characteristics | All relevant patient characteristics | All relevant patient characteristics | All relevant patient characteristics |
Multivariable model patient characteristics only | -Age | -Age | -Age | -Age |
| Â | -HRT use | -Obstetric history | -Fertility history | Â |
| Â | -BMI | -BMI | -PID | Â |
| Â | -Time since menopause | -Multiple pregnancies | -Ectopic pregnancy | Â |
| Â | -Diabetes | -Parity | -BMI | Â |
| Â | -Hypertension | -Diabetes | -Pelvic surgery | Â |
| Â | -Anticoagulants use | -Blood pressure | Â | Â |
| Â | -Previous cancer | Â | Â | Â |
| Â | -Thyroid dysfunction | Â | Â | Â |
Tests in multivariable model with tests | -TVS | -Cervical length | -CAT | -AFC |
| Â | -Hysteroscopy | -Fibronectin test | -HSG | -FSH |
| Â | Â | Â | -Laparoscopy | -AMH |
Subgroup analysis | -BMI* | Â | -Age* | -Age* |
| Â | -Diabetes | Â | -PID | -Duration subfertility* |
| Â | Â | Â | Duration subfertility* | -Type subfertility |
| Â | Â | Â | -Type subfertility | -BMI* |
| Â | Â | Â | -BMI* | Â |
| Â | Â | Â | -CAT | Â |
Diagnostic decision rules: | Â | Â | Â | Â |
1. Patient characteristics rule | histology if ca > 3% | Â | Â | Â |
2. Selective rule | TVS if ca > 3% → > 4 mm: histology |  |  |  |
3. Integrated rule | TVS and histology if ca > 3% | Â | Â | Â |
Decision analysis | Â | Â | -Patient characteristics | -Patient valuations |
| Â | Â | Â | -Tubal pathology | -IVF success |
Combined analyses | Â | Combination with progesterone | Combination with IVF outcome | Â |