From: Recruitment to a physical activity intervention study in women at increased risk of breast cancer
Inclusion Criteria |
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ALL of the following: |
Age 18–75 |
Sedentary |
Medically fit to exercise |
ECOG Performance Status 0–1 |
If on hormonal therapy, >2 months since starting or changing therapy |
and ANY of the following: |
Breast cancer survivor: |
History of Stage I, II, or III breast cancer |
(> 2 mos since completion of treatment) |
Increased risk of breast cancer: |
Gail model 5 year risk ≥1.67% |
Claus model lifetime risk >20% |
Previous breast biopsy showing high-risk lesion |
(e.g., atypical ductal hyperplasia or lobular neoplasia) |
History of appropriately treated ductal carcinoma in situ |
Known or suspected BRCA1 or BRCA2 gene mutation |
Exclusion Criteria |
Current or planned pregnancy |
Uncontrolled intercurrent illness |
Physical conditions that preclude daily walking |
(e.g., use of wheelchair, walker, cane, etc) |
History of cancer other than breast or non-melanoma skin cancer within 2 years preceding enrollment |
Metastatic or recurrent cancer |