Path plot. This graph shows the path of disease progression from the first (large black circles) to the final (end of the line) observation. The small dots along the line are at six month intervals and therefore represent time. The first assessment after patients received a neural transplantation are shown in red (black-only paths are controls) and any changes in disease trajectory post-transplant can be easily visualised. Different patterns of progression can also be seen; for example, some patients have an abrupt stop in the deterioration of the tapping score after a transplant (lower arrow), while others progressively perform fewer taps with a relatively stable UHDRS score (higher arrow).