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Table 1 Roland-Morris score decrease in the UK BEAM trial

From: Estimating the number needed to treat from continuous outcomes in randomised controlled trials: methodological challenges and worked example using data from the UK Back Pain Exercise and Manipulation (BEAM) trial

  Net benefit from intervention
Group at three months (95% CI) at 12 months (95% CI)
Exercise 1.36** (0.63–2.10) 0.39 (-0.41–1.19)
Manipulation 1.57*** (0.82–2.32) 1.01* (0.22–1.81)
Combined treatment 1.87*** (1.15–2.60) 1.30** (0.54–2.07)
  1. Adapted from UK BEAM BMJ 2004;329:1377–81
  2. * Significant at 5% level
  3. ** Significant at 1% level
  4. *** Significant at 0.1% level