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Table 3 NNTs derived from consensus thresholds for MIC for the RMDQ (95% CI)

From: Estimating the number needed to treat from continuous outcomes in randomised controlled trials: methodological challenges and worked example using data from the UK Back Pain Exercise and Manipulation (BEAM) trial

  Exercise Manipulation Combined
Three months       
Improvement, 5 points 8.2 (4.9 to 25.0) 5.2 (3.7 to 8.8) 4.8 (3.5 to 7.8)
Improvement, 30% 9.0 (5.0 to 44.5) 5.4 (3.8 to 9.9) 4.4 (3.3 to 7.0)
Benefit, 5 points 6.6 (4.1 to 16.6) 5.1 (3.6 to 9.3) 4.3 (3.1 to 7.0)
Benefit, 30% 5.1 (3.4 to 10.7) 5.0 (3.4 to 9.8) 3.3 (2.5 to 4.9)
12 months       
Improvement, 5 points * - 8.4 (5.0 to 28.6) 9.0 (5.2 to 37.8)
Improvement, 30% * - 8.0 (4.9 to 24.3) 7.1 (4.5 to 17.9)
Benefit, 5 points * - 7.8 (4.5 to 29.0) 7.2 (4.3 to 22.8)
Benefit, 30% * - 6.9 (4.1 to 21.1) 5.8 (3.7 to 13.2)
  1. * Analyses were not performed as no mean difference was reported between the exercise and best care groups at 12 months