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Table 2 For x > θ, observed screening test results, and observed and true disease status.

From: Bias in trials comparing paired continuous tests can cause researchers to choose the wrong screening modality

Test 1 Score Inequality Test 1 Result Test 2 Score Inequality Test 2 Result Signs and Symptoms Observed Disease Status True Disease Status
T 1 <θ - T 2 <θ -   - -
T 1 <θ - T 2 <θ - No signs - +
T 1 <θ - T 2 <θ - Signs + +
T 1 <θ - θ <T 2 <x -   - -
T 1 <θ - θ <T 2 <x -   + +
T 1 <θ - x <T 2 +   - -
T 1 <θ - x <T 2 +   + +
θ <T 1 <x - T 2 <θ -   - -
θ <T 1 <x - T 2 <θ -   + +
θ <T 1 <x - θ <T 2 <x -   - -
θ <T 1 <x - θ <T 2 <x -   + +
θ <T 1 <x - x <T 2 +   - -
θ <T 1 <x - x <T 2 +   + +
x <T 1 + T 2 <θ -   - -
x <T 1 + T 2 <θ -   + +
x <T 1 + θ <T 2 <x -   - -
x <T 1 + θ <T 2 <x -   + +
x <T 1 + x <T 2 +   - -
x <T 1 + x <T 2 +   + +
  1. The situations listed in this table are those where x > θ, i.e. that the test score is greater than the threshold that leads to referral to the invasive, yet sensitive and specific secondary test. The signs and symptoms column is left empty in those cases where the observed disease status does not depend on the development of signs or symptoms