Skip to main content

Table 1 Sample size calculation results

From: Simulating recurrent event data with hazard functions defined on a total time scale

  Number of patientsN0
θ d=2,p=0.2 d=8,p=0.5
0 160 184
0.1 204 226
0.2 252 274
0.3 296 320
0.4 340 366
0.5 380 422
  1. The simulation algorithm was applied to derive the number of individuals required for 80% power applying the robust two-sided Wald test at a 5% significance level for different frailty variances θ and risk-free intervals of length d (weeks) following an event with probability p. Each result was derived from 10000 simulation runs.
Back to article page

BMC Medical Research Methodology

ISSN: 1471-2288

Contact us