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Table 3 Measured and published sensitivity and specificity for each test in the integrated dataset before imputation, mean and 95 % CIs

From: A holistic comparative analysis of diagnostic tests for urothelial carcinoma: a study of Cxbladder Detect, UroVysion® FISH, NMP22® and cytology based on imputation of multiple datasets

  Measured Published
  Sensitivity, % (95 % CI) Specificity, % (95 % CI) Sensitivity, % (95 % CI) Specificity, % (95 % CI)
Cytology 45.5 (40.6–50.4) 96.3 (94.5–97.9) 56.1 (43.3–68.3) [18] 94.5 (91.9–96.5) [18]
NMP22 44.9 (37.4–52.3) 89.0 (86.5–91.5) 50.0 (37.4–62.6) [18] 88.0 (84.6–91.0) [18]
FISH 40.0 (22.7–52.3) 87.3 (83.7–91.6) 72 (69–75) [22] 83 (82–85) [22]
    61.9 [23] 89.7 [23]
    18 [24] 90 [24]
Cxbladder Detect 79.5 (71.1–87.8) 82.2 (79.2–85.0) 81.8 [18] 85.1 (fixed) [18]