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Table 5 Sensitivity and specificity of tests measured on the integrated, imputed dataset using different imputation methods

From: A holistic comparative analysis of diagnostic tests for urothelial carcinoma: a study of Cxbladder Detect, UroVysion® FISH, NMP22® and cytology based on imputation of multiple datasets

 

Supervised imputation

Unsupervised imputation

 

Sensitivity, %

Specificity, %

Sensitivity, %

Specificity, %

3NN

 

Cytology

44.94

96.35

44.94

96.35

NMP22

41.57

88.82

41.57

88.94

FISH

32.58

85.24

38.20

85.95

Cxbladder Detect

80.90

82.12

77.53

79.76

5NN

 

Cytology

44.94

96.35

44.94

96.35

NMP22

43.82

90.26

39.33

90.24

FISH

29.21

91.90

31.46

91.55

Cxbladder Detect

80.90

83.80

77.53

80.47

10NN

 

Cytology

44.94

96.49

44.94

96.35

NMP22

43.82

90.59

39.33

90.35

FISH

29.21

91.07

23.60

90.00

Cxbladder Detect

80.90

85.53

78.65

82.59

MLR

 

Cytology

44.94

96.35

44.94

96.56

NMP22

42.70

90.82

39.33

90.82

FISH

47.19

93.69

47.19

93.33

Cxbladder Detect

80.90

77.29

77.53

84.71

MLP

 

Cytology

44.94

96.35

44.94

96.35

NMP22

39.33

90.82

39.33

90.82

FISH

49.44

93.81

47.19

93.33

Cxbladder Detect

78.65

85.18

77.53

84.71