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Table 1 Clinical and demographic characteristics of men with mPC according to code definition

From: Measurement of skeletal related events in SEER-Medicare: a comparison of claims-based methods

   Base case definition   Alternative definition  
Overall Yes No   Yes No  
(N = 8997) (N = 4176) (N = 4821) (N = 3851) (N = 5146)
N (%)a N (%)b N (%)b P value N (%)b N (%)b P value
Age 1528 17.0 803 52.6 725 47.4 <0.01 794 52.0 734 48.0 <0.01
ᅟ66–70
ᅟ71–75 1801 20.0 908 50.4 893 49.6 895 49.7 906 50.3
ᅟ76–80 1995 22.2 942 47.2 1053 52.8 874 43.8 1121 56.2
ᅟ80< 3673 40.8 1523 41.5 2150 58.5 1288 35.1 2385 64.9
Race/Ethnicity 6762 75.2 3274 48.4 3488 51.6 <0.01 3001 44.4 3761 55.6 <0.01
ᅟNon-Hispanic White
ᅟNon-Hispanic Black 1282 14.3 445 34.7 837 65.3 411 32.0 871 68.0
ᅟHispanic 546 6.1 254 46.5 292 53.5 243 44.5 303 55.5
ᅟOther 407 4.4 203 49.9 204 50.1 196 48.2 211 51.8
Married 5216 58.0 2515 48.2 2701 51.8 <0.01 2385 45.7 2831 54.3 <0.01
Charlson Comorbidity Index 4871 54.1 2416 49.60 2455 50.40 <0.01 2280 46.81 2591 53.19 <0.01
ᅟ0
ᅟ1 1713 19.0 828 48.34 885 51.66 742 43.32 971 56.68
ᅟ2 777 8.6 333 42.86 444 57.14 289 37.19 488 62.81
ᅟ3+ 722 8.1 286 39.61 436 60.39 259 35.87 463 64.13
ᅟMissing 914 10.2 313 34.25 601 65.75 281 30.74 633 69.26
Poor Performance Status 1003 11.2 416 43.21 587 56.79 <0.01 350 37.34 653 62.66 <0.01
Gleason score        <0.01      <0.01
ᅟ2–6 206 2.3 78 37.86 128 62.14 77 37.38 129 62.62
ᅟ7 663 7.4 287 43.29 376 56.71 285 42.99 378 57.01
ᅟ8 771 8.6 355 46.04 416 53.96 335 43.45 436 56.55
ᅟ9 1224 13.6 577 47.14 647 52.86 557 45.51 667 54.49
ᅟ10 290 3.2 154 53.10 136 46.90 145 50.00 145 50.00
ᅟNot done/Unknown 5843 64.9 2725 46.64 3118 53.36   2452 41.96 3391 58.04  
Poorly differentiated tumor 3423 38.1 1563 45.66 1860 54.34 0.06 1390 40.61 2033 59.39 <0.01
High PSA at baseline 7298 81.1 3415 46.79 3883 53.21 0.14 3185 43.64 4113 56.36 <0.01
  1. Base case definition included codes identified under the ‘high specificity’ lists of RAD and SCC and codes under the ‘high sensitivity’ list of PF (in addition to all BS codes); Alternative definition included codes identified under the ‘high specificity’ list of PF and codes under the ‘high sensitivity’ lists of RAD and SCC (in addition to all BS codes). The Pearson χ2 was used to statistically test for significance of differences in the frequency distributions of categorical variables. A p value of <0.05 was considered statistically significant
  2. acolumn percent
  3. brow percent