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Table 2 Prevalence of SRE among mPC men according to the ‘base case’ and ‘alternative’ code definitions

From: Measurement of skeletal related events in SEER-Medicare: a comparison of claims-based methods

  Base case definition Alternative definition
  N % (of full cohort) % (of patients with at least 1 SRE) N % (of full cohort) % (of patients with at least 1 SRE)
PF 2202 24.5 % 52.7 % 1200 13.3 % 31.2 %
SCC 543 6 % 13 % 738 8.2 % 19.2 %
RAD 2736 30.4 % 65.5 % 2926 32.5 % 76 %
BSa 571 6.4 % 13.7 % 571 6.4 % 14.8 %
Any SRE 4176 46.4 % 100 % 3851 42.8 % 100 %
  1. Base case definition included codes identified under the ‘high specificity’ lists of RAD and SCC and codes under the ‘high sensitivity’ list of PF (in addition to all BS codes)
  2. Alternative definition included codes identified under the ‘high specificity’ list of PF and codes under the ‘high sensitivity’ lists of RAD and SCC (in addition to all BS codes)
  3. SRE Skeletal Related Event, PF Pathological Fracture, SCC Spinal Cord Compression, RAD Bone Palliative Radiotherapy; BS Bone surgery
  4. aOnly one set of codes was used for bone surgery