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Table 4 Results of the meta-analysis of the diagnostic tests for visceral leishmaniasis

From: A general framework for comparative Bayesian meta-analysis of diagnostic studies

 

Parasitology as Gold Standard

No Gold Standard

 

Model 1

Model 2

Model 3

Model 4

Model 5

Parameter

Estimate

Estimate

Estimate

Estimate

Estimate

S1 (R1)

94.2

95.5

94.8

95.9

94.7

S1 (R2)

85.2

84.0

86.5

84.6

88.1

S2 (R1)

95.7

97.2

96.4

96.3

96.4

S2 (R2)

94.4

93.5

95.4

96.1

96.5

C 1

78.6

75.5

78.3

90.2

91.0

C 2

80.1

80.9

81.5

93.0

94.1

SD12 (R1)

1.5

1.7

1.6

0.4

1.7

SD12 (R2)

9.2

9.6

8.9

11.5

8.4

C D12

1.5

5.3

3.2

2.8

3.1

SRR12 (R1)

1.02

1.02

1.02

1.00

1.02

SRR12 (R2)

1.11

1.12

1.10

1.14

1.10

C RR12

1.02

1.07

1.04

1.03

1.03

SOR12 (R1)

1.3

1.7

1.5

1.1

1.6

SOR12 (R2)

2.7

2.8

3.3

4.7

3.9

C OR12

1.1

1.4

1.2

1.5

1.7

  1. S i and C i : sensitivity and specificity of Test i; SD12 and DD12: difference in sensitivity and specificity between Test 1 and Test 2; SRR12 and DRR12: relative sensitivity and specificity of Test 1 compared to Test 2 as a relative risk; SOR12 and DOR12: relative sensitivity and specificity of Test 1 compared to Test 2 expressed as an odds-ratio. R1 and R2 indicate estimates obtained for East-Africa and the rest of the world, respectively