|
Bronchiolitis - inpatient outcomes
|
|---|
|
Clinical score
|
Length of stay
|
|---|
|
Time point for clinical score assessment
|
Patients (studies)
|
Effect estimate SMD (95 % CI)
|
I2 (%)
|
Quality of evidence
|
Patients (studies)
|
Effect estimate MD (95 % CI)
|
I2 (%)
|
Quality of evidence
|
|---|
|
Glucocorticoids vs. placebo
|
|
At 1–3 days
|
113 (4)
|
−0.74 (−1.48,1.01)
|
70
|
Low
|
633 (8)
|
−0.18 (−0.39,0.04)
|
16
|
High
|
|
Bronchodilator vs. placebo
|
|
No data
|
349 (6)
|
0.06 (−0.27,0.39)
|
0
|
Moderate
|
|
Epinephrine vs. placebo
|
|
At 60 min
|
232 (2)
|
−0.04 (−0.49, 0.40)
|
46
|
Moderate
|
292 (2)
|
−0.35 (−0.87,0.17)
|
0
|
Moderate
|
|
Epinephrine vs. bronchodilator
|
|
At 60 min
|
248 (4)
|
−0.79 (−1.45,-0.13)
a
|
79
|
Low
|
261 (4)
|
−0.28 (−0.46,-0.09)
a
|
0
|
Moderate
|
|
At 120 min
|
140 (1)
|
−0.52 (−0.68,-0.18)
a
|
NA
|
Low
|
|
3 % hypertonic saline vs. 0.9 % saline
|
|
At 1–3 days
|
183 (3)
|
−0.84 (−1.39,-0.30)
|
66
|
Low
|
282 (4)
|
−1.16 (−1.55,-0.77)
a
|
0
|
Moderate
|
|
At 3–10 days
|
156 (3)
|
−1.08 (−2.47,0.31)
|
93
|
Moderate
|
|
Chest physiotherapy vs. standard care or other drainage/breathing technique
|
|
At 1–3 days
|
87 (1)
|
−0.55 (−0.98,-0.12)
a
|
NA
|
Low
|
172 (3)
|
0.07 (−0.58,0.73)
|
0
|
Low
|
|
At 3–10 days
|
91 (2)
|
−0.14 (−0.81,0.53)
|
59
|
Low
|
-
afavours 1st intervention; NA - not applicable; SMD - standardized mean difference
- Outcomes in bold indicate statistical significance
