From: Creating a literature database of low-calorie sweeteners and health studies: evidence mapping
Outcome group (number of studies) | Form of LCS intervention (number of studies) | Study design (number of studies) | Baseline health (number of studies) | Age group (mean) | Sample size (mean) | Country (number of studies) |
---|---|---|---|---|---|---|
Appetite (84) | Beverage (54), Food or meal (22), Supplement or oral rinse (8) | RCT-c (48), RCT-p (22), nRCT-c (11), nRCT-p (1), Single arm (1), unclear (1) | Healthy (66), Overweight/Obese (9), Mixed/other (9) | 24.1 | 52 | United States (41), Europe (31), Canada (9), Australia (3) |
Alter energy sensing (75) | Beverage (58), Food or meal (10), Supplement or oral rinse (7) | RCT-c (48), RCT-p (10), nRCT-c (13), Single arm (3), unclear (1) | Healthy (54), Overweight/Obese (2), Diabetic (1), Mixed/other (18) | 26.1 | 47 | United States (43), Europe (23), Canada (7), Asia (2) |
Body weight or body composition (35) | Beverage (14), Food or meal (13), Supplement or oral (8) | RCT-c (7), RCT-p (25), nRCT-c (2), nRCT-p (1) | Healthy (17), Overweight/Obese (8), Diabetic (5), Mixed/other (5) | 35.6 | 92 | United States (19), Europe (10), Asia (3), Africa (2), NR (1) |
Body weight or body composition (17) cohort | Beverage (17) | Cohort (17) | Healthy (17) | 32.0 | 15,430 | United States (1), Europe (1) |
Dietary Intake (62) | Beverage (39), Food or meal (19), Supplement or oral rinse (4) | RCT-c (33), RCT-p (20), nRCT-c (5), nRCT-p (2) Single arm (2) | Healthy (43), Overweight/Obese (12), Diabetic (1), Mixed/other (6) | 27.2 | 39 | United States (29), Europe (22), Canada (9), Australia (1), NR (1) |
Glycemic (76) | Beverage (42), Food or meal (19), Supplement or oral rinse (14), Not reported (1) | RCT-c (51), RCT-p (21), nRCT-c (2), Single arm (2) | Healthy (39), Overweight/Obese (8), Diabetic (17), Mixed/other (12) | 37.6 | 31 | United States (28), Europe (27), Asia (8), Australia (7), Canada (3), Africa (1), Not reported (2) |