Scenario | Dataset |
n
| Test |
---|
| | | Cox | Joint | Perm. | Comb. |
---|
A (null) | GOG111 | 1000 | 5.2 | 5.3 | 4.9 | 5.3 |
| PATCH1 | 1000 | 5.0 | 4.9 | 5.2 | 4.8 |
| ICON7 | 1000 | 4.8 | 4.9 | 5.2 | 4.9 |
B (PH) | GOG111 | 652 |
9
2
.
9
| 87.2 |
8
6.7
| 91.0 |
| PATCH1 | 1280 |
9
2
.
6
|
8
6.9
| 87.7 | 90.2 |
| ICON7 | 1240 |
9
1
.
9
|
8
6.6
| 88.3 | 89.8 |
C (early) | GOG111 | 310 |
7
2.5
| 91.5 |
9
2
.
1
| 90.0 |
| PATCH1 | 450 |
7
4.4
| 88.8 |
9
1
.
9
| 89.2 |
| ICON7 | 522 |
3
6.9
|
9
8
.
7
| 92.4 | 89.5 |
D (late) | GOG111 | 560 | 92.7 |
9
6
.
1
|
8
0.5
| 90.3 |
- Values in table are percentages of 10,000 (scenario A) or 5,000 (scenarios B–D) simulated datasets in which each of four tests was significant at the 5 percent level. The datasets were simulated to mimic data from three randomized controlled trials with varying sample size (n). Values in bold (or italic) type indicate the most (or least) powerful among the four tests for the given scenario and dataset
- Abbreviations: Joint joint test [1], Perm. permutation test, Comb. combined test