Table 1 Relative efficiency of single- and mixed-strain designs for each type of effect. The numbers of cages are the median required amounts to achieve 80 % power in the mixed- and single-strain designs. Test statistics are based on a Mann Whitney test (n = 52). See Additional file 1: Tables S2–S4 for details
Effect | Median number of cages in the single-strain design (inter-quartile range) | Median number of cages needed for equivalent power in the mixed-strain design (inter-quartile range) | Test Statistics |
|---|---|---|---|
Enrichment | 252 (96 - >600) | 66 (30–456) | Z = 1.74; p = 0.081 |
Strain | 30 (12–108) | 12 (12–42) | Z = 2.18; p = 0.029 |
Strain*Enrichment | 282 (96 - >600) | 120 (54–258) | Z = 1.96; p = 0.049 |