Table 1 Demographic characteristics and comorbidity status of the Full Cohort at baseline
Low potency n (%) | High potency n (%) | Absolute standardized differences | |
|---|---|---|---|
264,947 (100.0) | 139,182 (100.0) | ||
Age, mean (SD)a | 65.6 (10.9) | 64.5 (11.3) | 0.098 |
Male sex | 118,262 (44.6) | 74,702 (53.7) | 0.181 |
At least 5 medical outpatient visits | 170,234 (64.3) | 77,032 (55.4) | 0.182 |
At least 1 hospitalisation | 59,591 (22.5) | 45,777 (32.9) | 0.234 |
Myocardial infarction | 15,056 (5.7) | 18,899 (13.6) | 0.270 |
Stroke | 7150 (2.7) | 5480 (3.9) | 0.069 |
Hypertension | 110,508 (41.7) | 59,705 (42.9) | 0.024 |
Hypercholesterolemia | 88,458 (33.4) | 47,005 (33.8) | 0.008 |
Peripheral vascular disease | 5446 (2.1) | 3338 (2.4) | 0.023 |
Congestive heart failure | 11,337 (4.3) | 8830 (6.3) | 0.092 |
Coronary artery bypass graft | 3589 (1.4) | 3189 (2.3) | 0.070 |
Percutaneous coronary intervention | 7742 (2.9) | 14,089 (10.1) | 0.295 |
Dispensation of loop diuretics | 16,612 (6.3) | 10,188 (7.3) | 0.042 |
Dispensation of calcium blockers | 64,569 (24.4) | 32,192 (23.1) | 0.029 |
Dispensation of beta-blockers | 77,669 (29.3) | 49,147 (35.3) | 0.128 |
Dispensation of angiotensin receptor blockers | 35,741 (13.5) | 25,325 (18.2) | 0.129 |
Dispensation of angiotensin converting enzyme inhibitors | 52,563 (19.8) | 36,030 (25.9) | 0.144 |
At least 5 different drugs dispensed | 151,395 (57.1) | 84,503 (60.7) | 0.073 |