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Table 1 Number of case-control pairs in each stratum and time period with gene expression data X g,p

From: A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle

Strata Year before diagnosis (time period)
Detection category Lymph node status 5-3 (3) 2 (2) 1 (1)
Screen-detected cancersa With spread 41 11 6
Without spread 118 42 43
Interval cancersb With spread 28 9 6
Without spread 30 15 10
Clinical cancersc With spread 11 8 10
Without spread 28 12 13
  1. aDiagnosed at a screening visit
  2. bDiagnosed within 2 years of a screening visit
  3. cDiagnosed clinically and did not attend the screening program or diagnosed clinically more than 2 years after a screening visit