A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle

Table 2 P-values obtained when testing whether there are more genes in the curve groups than what is expected by chance in different strata

p-value
Curve group	Screen-detected, interval, and clinical cancers with spread	Screen-detected, interval, and clinical cancers without spread	Screen-detected and interval cancers with spread	Screen-detected and interval cancers without spread
Global	0.78	0.27	0.01*	0.20
123	0.61	0.23	0.02*	0.39
132	0.49	0.13	0.008*	0.11
312	0.88	0.18	0.13	0.11
321	0.41	0.74	0.02*	0.66
231	0.74	0.68	0.50	0.57
213	0.58	0.17	0.48	0.13

ISSN: 1471-2288