Heterogeneity scenario | Methods | β = 0 | β = −0.7 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
t * = 5 True rmstD = 0 | t * = 10 True rmstD = 0 | t * = 5 True rmstD = −0.3 | t * = 10 True rmstD = 0.3 | ||||||||||
Bias | ESE | ASE | Bias | ESE | ASE | Bias | ESE | ASE | Bias | ESE | ASE | ||
(σ2,τ2) = (0.01;0.01) | Naïve Kaplan-Meier | 0.00 | 0.12 | 0.11 | 0.00 | 0.28 | 0.24 | 0.00 | 0.12 | 0.11 | 0.00 | 0.28 | 0.24 |
Pooled Kaplan-Meier | 0.00 | 0.12 | 0.13 | 0.01 | 0.29 | 0.30 | 0.01 | 0.12 | 0.13 | −0.05 | 0.29 | 0.29 | |
Pooled Exponential | 0.00 | 0.10 | 0.11 | 0.00 | 0.27 | 0.28 | 0.40 | 0.12 | 0.12 | 0.07 | 0.30 | 0.30 | |
Peto-quintile | 0.00 | 0.11 | 0.10 | 0.00 | 0.24 | 0.21 | 0.02 | 0.11 | 0.10 | −0.19 | 0.24 | 0.21 | |
(σ2,τ2) = (0.01;0.10) | Naïve Kaplan-Meier | 0.00 | 0.19 | 0.11 | 0.02 | 0.50 | 0.24 | 0.00 | 0.19 | 0.11 | 0.00 | 0.48 | 0.24 |
Pooled Kaplan-Meier | 0.01 | 0.19 | 0.18 | 0.02 | 0.50 | 0.46 | 0.00 | 0.19 | 0.18 | −0.05 | 0.48 | 0.46 | |
Pooled Exponential | 0.00 | 0.19 | 0.17 | 0.01 | 0.49 | 0.45 | 0.39 | 0.20 | 0.18 | 0.05 | 0.50 | 0.47 | |
Peto-quintile | 0.00 | 0.18 | 0.10 | 0.01 | 0.43 | 0.22 | 0.02 | 0.18 | 0.10 | −0.18 | 0.42 | 0.22 | |
(σ2,τ2) = (0.10;0.01) | Naïve Kaplan-Meier | 0.00 | 0.12 | 0.11 | 0.00 | 0.28 | 0.24 | 0.00 | 0.12 | 0.11 | −0.01 | 0.27 | 0.24 |
Pooled Kaplan-Meier | 0.00 | 0.12 | 0.13 | 0.00 | 0.29 | 0.29 | 0.00 | 0.12 | 0.13 | −0.07 | 0.28 | 0.29 | |
Pooled Exponential | 0.00 | 0.10 | 0.11 | 0.00 | 0.27 | 0.28 | 0.38 | 0.12 | 0.12 | 0.04 | 0.30 | 0.31 | |
Peto-quintile | 0.00 | 0.11 | 0.10 | 0.00 | 0.24 | 0.21 | 0.00 | 0.11 | 0.10 | −0.21 | 0.25 | 0.22 | |
(σ2,τ2) = (0.10;0.10) | Naïve Kaplan-Meier | −0.01 | 0.19 | 0.11 | −0.01 | 0.46 | 0.24 | 0.00 | 0.20 | 0.11 | 0.01 | 0.49 | 0.24 |
Pooled Kaplan-Meier | −0.01 | 0.19 | 0.18 | −0.02 | 0.47 | 0.45 | 0.00 | 0.20 | 0.18 | −0.05 | 0.48 | 0.45 | |
Pooled Exponential | −0.01 | 0.18 | 0.17 | −0.01 | 0.45 | 0.44 | 0.38 | 0.20 | 0.18 | 0.05 | 0.50 | 0.46 | |
Peto-quintile | −0.01 | 0.18 | 0.10 | −0.01 | 0.41 | 0.22 | 0.01 | 0.19 | 0.10 | −0.18 | 0.44 | 0.22 |