Table 4 Pharmaceuticals characteristics of studies involving drug therapy (n = 35)
From: Academic pediatric clinical research: factors associated with study implementation duration
Pharmaceutical characteristics | Studies involving drug therapy (n = 35) |
|---|---|
Inclusion of children under 6 years old | 26 (74) |
Randomized study | 26 (74) |
Duration of treatment, days | 60 [5;365] |
Blinded investigator | 16 (46) |
Blinded patient | 17 (49) |
Control group | |
Standard treatment | 10 (29) |
Placebo | 13 (37) |
No control group | 12 (34) |
At least a drug of the study not approved in pediatric population | 10 (33) |
Age-appropriate formulation | |
Appropriate | 26 (74) |
Intermediate at least for one drug of the study | 3 (9) |
Inappropriate at least for one drug of the study | 6 (17) |
Route of administration | |
Enterally at least for one drug of the study | 19 (54) |
Parenterally | 16 (46) |