TY - JOUR AU - Jacob, Louis AU - Uvarova, Maria AU - Boulet, Sandrine AU - Begaj, Inva AU - Chevret, Sylvie PY - 2016 DA - 2016/06/02 TI - Evaluation of a multi-arm multi-stage Bayesian design for phase II drug selection trials – an example in hemato-oncology JO - BMC Medical Research Methodology SP - 67 VL - 16 IS - 1 AB - Multi-Arm Multi-Stage designs aim at comparing several new treatments to a common reference, in order to select or drop any treatment arm to move forward when such evidence already exists based on interim analyses. We redesigned a Bayesian adaptive design initially proposed for dose-finding, focusing our interest in the comparison of multiple experimental drugs to a control on a binary criterion measure. SN - 1471-2288 UR - https://doi.org/10.1186/s12874-016-0166-7 DO - 10.1186/s12874-016-0166-7 ID - Jacob2016 ER -